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Thin layer chromatography is done exactly as it says - using a thin, uniform layer of silica gel or alumina coated onto a piece of glass, metal or rigid plastic. Objective the purpose of this experiment is to identify an unknown proprietary drug using thin-layer chromatography. The unknowns behavior in thin-layer chromatography will be compared with that of its possible component analgesics. Thin layer chromatography, or tlc, is a method for analyzing mixtures by separating the compounds in the mixture. Thin layer chromatography (t lc) is a chromatographic technique used to se parate the components of a mixture using a thin stationary phase supported by an inert backing. It may be performed on the analytical scale as a means of monitoring the progress of a reaction, or on the preparative scale to purify small amounts of a compound. Thin layer chromatography (tlc) is similar to paper chromatography but instead of paper, the stationary phase is a thin layer of an inert substance (eg silica) supported. What is thin layer chromatography? Thin layer chromatography is a technique used to isolate non-volatile mixtures. The experiment is conducted on a sheet of aluminium foil, plastic, or glass which is coated with a thin layer of adsorbent material. thin-layer chromatography is a chromatography technique that separates pigments, identifying molecules. While it has many applications in a wide variety of industries, it is a particularly important technique used in forensic labs, helping scientists determine if two pieces of text were written by the same ink, which can often be an indicator of fraud. Abstract there has been a tendency to discount thin-layer chromatography (tlc) in recent years because of the availability of high-performance liquid chromatography (hplc) methods that appeared to offer greater versatility and ease of quantification, amongst other reasons. However, tlc has made a comeback, largely because of the high reproducibility and lower costs of commercial pre-coated.
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